Who We Are
ENSEM Therapeutics (“ENSEM”) is a Boston-based, preclinical stage biopharmaceutical company focused on
high value and difficult-to-drug
targets in oncology to address unmet medical needs. The name ENSEM symbolizes innovations via the
integration of groundbreaking technologies
to decipher structural ENSEMbles and kinetics for drug design. The company’s mission is to discover,
develop, and commercialize transformative
oncology therapies for patients, while leading the advancement of AI-driven structural ensemble and
computational drug design.
Cryptic binding pockets: A small molecule (yellow) induces protein conformational changes (blue)
and the opening of a cryptic pocket.